CRC 870

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Context-dependent modulation of mechanosensory circuits

Principal Investigators:

Sensory systems require the implementation of context-dependent adaptability mechanisms to constantly meet the demands during a particular behavior. The aim of this proposal is to decipher how corollary discharges (CD) from the vocal motor system shape the responses of the auditory sensory system from the level of the animal’s periphery up to the central nervous system. The general hypothesis is that duration, and not frequency of the vocalization, is the predominant parameter transmitted by CD. Auditory sensitivity is thus likely reduced during different motor behavioral states (vocalization vs non-vocalization) in order to decrease the deteriorating effects of reafferent sensory stimulation.