CRC 870

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Control of Sensory-Motor Transformation by Corollary Activity during Self-Motion

Principal Investigators:

During self-motion in vertebrates, intrinsic locomotor efference copies directly elicit compensatory eye movements and suppress horizontal semicircular canal sensory inputs. In a multi-methodological, approach in Xenopus laevis, this proposal aims to reveal the functional principles that govern the interaction between intrinsic corollary activity and self-motion related extrinsic sensory signals at the cellular and network level. The expected outcome will increase the understanding of how context-dependent behavioral states (active locomotion - passive body motion) influence sensory-motor information processing through an immanent control of self-generated reafferent multisensory signals.