CRC 870

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Neurogenetic dissection of the visual motion detection circuitry in the fruit fly

The detection of visual motion is a fundamental computation of any visual system. An algorithmic model, the Reichardt detector, accounts for this by multiplying adjacent inputs after asymmetric temporal filtering. However, the neural circuits performing these computations are not well understood in any species. Studying this problem in Drosophila, we have defined the input and the output neurons of the local circuits. We now aim to identify those neuron types in between which convey delayed and non-delayed signals onto the dendrites of the output neurons and to explore the biophysical mechanisms that underlie their integration to produce direction-selective motion signals.